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pholcodine

CAS 509-67-1
15

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Pholcodine is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Pholcodine is a morphinan alkaloid with potent opioid antitussive activity, available by prescription in most EU member states. It carries the typical opioid risk profile including CNS depression, sedation, and respiratory depression, particularly in combination with other CNS depressants. It has no functional role in cosmetic formulations and is prohibited under EU cosmetic regulations as a pharmacologically active substance without cosmetic safety assessment.

Known concerns

  • Opioid antitussive — strictly regulated pharmaceutical
  • CNS and respiratory depression risk
  • Prohibited in EU cosmetic products

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.