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Conditioning Agent

PLUMBAGO ZEYLANICA ROOT EXTRACT

Updated
30

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A leadwort root extract carrying plumbagin — a naphthoquinone with documented skin irritation, cytotoxicity to keratinocytes, and oral toxicity (LD50 ~65 mg/kg). Not appropriate as a routine cosmetic ingredient.

Function

SKIN CONDITIONING

Skin benefits

  • Antimicrobial activity (limited topical use)

Known concerns

  • Plumbagin-driven skin irritation and blistering
  • Keratinocyte cytotoxicity
  • Pesticidal/antifertility activity in animal studies
  • Not appropriate as routine cosmetic ingredient

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.