Conditioning Agent
NAPROXEN
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Naproxen is a pharmaceutical NSAID used in cosmetics for skin conditioning but is subject to EU restrictions as a drug-like substance with systemic toxicity concerns.
Naproxen (CAS 22204-53-1, (S)-2-(6-methoxy-2-naphthyl)propionic acid) is a non-steroidal anti-inflammatory drug (NSAID). While it has skin conditioning properties, it is a pharmaceutical substance with known systemic toxicity (gastrointestinal, cardiovascular, renal effects). The EU cosmetics regulation flags substances that deplete the ozone layer for restrictions, and drug-like substances with systemic profiles are generally incompatible with cosmetic use in the EU. Naproxen use in cosmetics is highly restricted and discouraged.
Function
Skin benefits
- Skin conditioning
Known concerns
- Pharmaceutical NSAID with systemic toxicity
- Gastrointestinal risk
- Cardiovascular risk
- Not approved as cosmetic active in EU
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related conditioning agents
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.