Conditioning Agent
SR-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A recombinant protein explicitly tied to botulinum neurotoxin biology. Even if topical exposure and skin penetration are limited, that is not a category that earns blind trust.
sr-Clostridium Botulinum Polypeptide-1 is described as a recombinant protein whose starting gene is synthesized to be identical to the gene coding for Botulinum Neurotoxin Type A derived from Clostridium botulinum. Its very large size may reduce skin penetration, but the biological identity still raises obvious caution around potency, manufacturing control, and the lack of strong independent cosmetic safety data. No explicit ban is listed here, yet the toxicology context is serious enough to keep the score low.
Function
Skin benefits
- May help reduce the look of expression lines
- Skin conditioning
Known concerns
- Botulinum-neurotoxin-derived protein concept
- Very limited independent cosmetic safety data
- Biologically potent source sequence raises manufacturing and safety questions
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related conditioning agents
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.