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Botanical Extract

POLYGONUM MULTIFLORUM EXTRACT

Updated
32

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Fo-ti root extract — well-documented for severe oral hepatotoxicity. Topical risk is lower but anthraquinone load and regulator warnings make this one to avoid in skincare.

Function

SKIN CONDITIONING

Skin benefits

  • Stilbene glycoside antioxidants
  • Traditional hair-darkening reputation
  • Anthraquinone polyphenols

Known concerns

  • Documented severe hepatotoxicity in oral use
  • Cautionary statements issued by China, Australia, UK, Japan, Canada
  • Anthraquinones (emodin, rhein) implicated in liver injury
  • Immune-mediated liver damage reported
  • Topical safety margin not well established

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.