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POLYGONUM MULTIFLORUM ROOT WATER

CAS -
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

He shou wu root water, a classic Chinese herb for hair and skin vitality.

Polygonum multiflorum (He Shou Wu) contains stilbene glycosides (piceid, polydatin) and anthraquinones. Multiple pharmacovigilance reports from China, Korea, and other Asian countries have documented drug-induced liver injury (DILI) associated with oral consumption. The compound emodin-8-O-beta-D-glucoside is implicated. Korea's MFDS has issued safety warnings; the EU SCCS has not issued a specific opinion but the ingredient warrants caution.

Skin benefits

  • traditional hair and skin tonic use
  • antioxidant

Known concerns

  • documented hepatotoxicity (liver injury) from oral use
  • stilbene glycosides may cause liver enzyme elevations
  • restricted/monitored in several Asian markets
  • EU safety data insufficient — precautionary approach recommended

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.