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POLYQUATERNIUM-18

CAS -
75

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A cationic polymeric conditioning agent used primarily in hair care products to improve combability and reduce static. Generally considered safe with low irritation potential.

Polyquaternium-18 is a cationic polymeric quaternary ammonium compound (INN: copolymer of dimethylallylammonium chloride and acrylamide) used as an antistatic agent and hair-conditioning polymer in cosmetic formulations. While not specifically restricted under EU Regulation (EC) No 1223/2009, polymeric quaternary ammonium compounds may occasionally show sensitization potential at high concentrations; the Scientific Committee on Consumer Safety (SCCS) has assessed similar polyquaterniums with favorable conclusions at typical use concentrations.

Skin benefits

  • Provides antistatic and conditioning effects
  • Improves combability and reduces flyaway

Known concerns

  • Possible sensitization at high concentrations (uncommon)
  • Not typically used in skin-care leave-on products — primarily a hair-care ingredient

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.