Skip to content

Skin Conditioning

R-(METHIONYL SH-POLYPEPTIDE-8 DECAPEPTIDE-40)

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A recombinant fusion peptide combining methionyl polypeptide-8 with decapeptide-40, used at trace levels for anti-aging claims. Public toxicology data is limited.

Function

SKIN CONDITIONINGSKIN PROTECTING

Skin benefits

  • Recombinant skin-signaling peptide
  • Used at trace levels in serums
  • Marketed for anti-aging and barrier support

Known concerns

  • Recombinant proteins can carry host-cell residual concerns
  • No public CIR/SCCS opinion
  • Possible immunogenicity in atopic users
  • Stability and shelf-life challenges

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related skin conditionings

65
(ANGELICA GIGAS/CNIDIUM OFFICINALE/PAEONIA LACTIFLORA) ROOT EXTRACT
Skin Conditioning
 65
(SH-OLIGOPEPTIDE-78 S-FRUIT FLY OLIGOPEPTIDE-1) PEPTIDES
Skin Conditioning
 65
(SH-PENTAPEPTIDE-10 6-AMINOCAPROOYL SH-PENTAPEPTIDE-11) SP
Skin Conditioning
 65
ABELMOSCHUS MANIHOT CALLUS EXTRACELLULAR VESICLES
Skin Conditioning
 65
ABIES BALSAMEA EXTRACT
Skin Conditioning
 65
ACEFYLLINE METHYLSILANOL MANNURONATE
Skin Conditioning
 65
ACETAMINO METHYLSULFONYLBUTYROYL DIPEPTIDE-57
Skin Conditioning
 65
ACETOBACTER/SACCHAROMYCES/SALIX ALBA BARK/PELARGONIUM GRAVEOLENS FLOWER/(CARICA PAPAYA/CITRUS LIMON) FRUIT/(CAMELLIA SINENSIS/CARICA PAPAYA) LEAF/(CHICORY/LICORICE) ROOT/HELIANTHUS TUBEROSUS TUBER/LACTARIUS DELICIOSUS/ARMILLARIA MELLEA/CYMBOPOGON SCHOENANTHUS FERMENT FILTRATE
Skin Conditioning

Check your shelf

Find R-(METHIONYL SH-POLYPEPTIDE-8 DECAPEPTIDE-40) in your products.

Scan any cosmetic product with LuxSense to see if it contains R-(METHIONYL SH-POLYPEPTIDE-8 DECAPEPTIDE-40) and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.