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Skin Conditioning

S-RNA-5

Updated
65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic 22-nucleotide RNA strand used in advanced anti-ageing cosmetics to influence cellular renewal pathways. Limited long-term safety data and regulatory uncertainty in the EU justify a cautious yellow-tier rating.

Skin benefits

  • Designed to target specific gene expression pathways
  • Used in advanced anti-ageing skincare
  • Stable at typical formulation pH

Known concerns

  • Synthetic RNA-based ingredients have limited long-term topical safety data
  • Potential off-target effects require careful evaluation
  • Regulatory status uncertain in EU for some applications
  • Activity heavily dependent on delivery and stability

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.