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Skin Conditioning

SH-OLIGOPEPTIDE-73 AMIDE TRIFLUOROACETATE

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic signal peptide (oligopeptide-73) supplied as the trifluoroacetate salt. Trendy active in premium serums; the trifluoroacetate counter-ion is PFAS-adjacent which raises environmental concerns.

Function

ANTIOXIDANTHUMECTANTSKIN PROTECTING

Skin benefits

  • Synthetic peptide for skin-conditioning claims
  • Possible signaling activity
  • Trendy active in premium serums

Known concerns

  • Trifluoroacetate counter-ion — environmental persistence concerns (PFAS-adjacent)
  • Limited published safety data on this specific peptide
  • Marketing claims often outpace clinical evidence
  • Synthetic; expensive

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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Same plant / compound family

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.