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Skin Conditioning

SYMPHYTUM OFFICINALE CALLUS CULTURE EXTRACT

Updated
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Comfrey plant cells grown in lab culture, then extracted. Source of allantoin and phenolics. Comfrey carries pyrrolizidine alkaloid concerns even via skin, so caution applies.

Function

SKIN CONDITIONING

Skin benefits

  • Allantoin-rich soothing
  • Antioxidant phenolics
  • Skin conditioning

Known concerns

  • Comfrey contains hepatotoxic pyrrolizidine alkaloids
  • Topical PA absorption is documented
  • Callus culture may reduce but not eliminate PAs
  • Variable batch composition

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.