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Skin Conditioning

SYMPHYTUM OFFICINALE LEAF EXTRACT

CAS 84696-05-9 Updated
65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Comfrey leaf extract used for soothing and repair, naturally rich in allantoin. Cosmetic-grade extracts must be PA-depleted, since pyrrolizidine alkaloids in raw plant are hepatotoxic.

Function

SKIN CONDITIONING

Skin benefits

  • Allantoin-rich; soothes and supports skin repair
  • Traditional skin-conditioning botanical
  • Calming for irritated areas

Known concerns

  • Pyrrolizidine alkaloids must be removed for cosmetic safety
  • EU restricts oral use; topical leaf extract preferred over root
  • Limited modern human safety data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.