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Skin Conditioning

TETRAPEPTIDE-111

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A four-amino-acid synthetic peptide used as a skin-conditioning signal. Trace use levels and benign chemistry; limited public data.

Tetrapeptide-111 is a synthetic four-amino-acid peptide marketed as a skin-conditioning active. Cosmetic peptides of this class are used at parts-per-million levels and are generally non-sensitizing and rapidly metabolised on the skin. There is no SCCS or CIR opinion; toxicology and efficacy rest on supplier dossiers. Independent published evidence for its specific actions is limited.

Function

SKIN PROTECTING, SKIN CONDITIONING - HUMECTANT

Skin benefits

  • Targeted skin-conditioning peptide
  • Used at parts-per-million levels
  • Low irritation potential

Known concerns

  • Limited public toxicology data
  • Efficacy claims supplier-driven
  • No SCCS or CIR opinion

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.