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Skin Conditioning

TETRAPEPTIDE-68

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic four-amino-acid peptide used as a skin-conditioning active. Low-risk by class, specific evidence is thin.

Tetrapeptide-68 is a defined-sequence synthetic peptide of four amino acids used in skin-conditioning formulations. Tetrapeptides in personal care typically have favorable safety profiles — too large to readily penetrate skin, rapidly degraded by surface enzymes into amino acids, and rarely sensitizing. No specific CIR or SCCS opinion has been issued. Independent peer-reviewed efficacy data is sparse; most claims come from supplier in vitro and small consumer-panel studies. Treated as low-risk, low-evidence.

Function

SKIN CONDITIONING

Skin benefits

  • Skin conditioning
  • Low irritation
  • Defined synthetic sequence

Known concerns

  • Limited independent data
  • No regulatory dossier
  • Supplier-driven claims

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.