Other
tramazoline
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Tramazoline is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.
Tramazoline is a synthetic imidazoline derivative functioning as an alpha-adrenergic receptor agonist with vasoconstrictive activity, registered for pharmaceutical use in nasal decongestant formulations. It is not listed in any EU cosmetic positive list and does not fall under any Annex restriction because it has no legitimate cosmetic function. The SCCS has not assessed this substance, and its use in cosmetic products would constitute an unauthorized drug substance under EU cosmetic regulation.
Known concerns
- Prescription pharmaceutical — alpha-adrenergic agonist
- Not authorized in EU cosmetics under Regulation (EC) No 1223/2009
- Cardiovascular effects including hypertension and arrhythmias with systemic exposure
- No cosmetic function or safety assessment by SCCS
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.