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Triparanol (INN)

CAS 78-41-1
12

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Triparanol (inn) is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Triparanol (INN) was a synthetic triparanolamine derivative marketed as a cholesterol-lowering agent but was withdrawn from the market in the 1960s due to severe adverse effects including cataracts, corneal opacity, and hair loss. It has no established cosmetic use and is not permitted in the EU's cosmetic ingredient database. Its safety for any topical application is categorically rejected by historical pharmaceutical data.

Known concerns

  • Drug withdrawn from market due to toxicity
  • Causes cataracts and corneal opacities
  • No cosmetic application — not assessed for topical safety

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.