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VANILLYLIDENE PENTANEDIONE

CAS 91418-45-0
72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Vanillylidene Pentanedione is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Vanillylidene pentanedione (vanillin analog with a diketone backbone) is used as a fragrance and flavoring ingredient with a sweet, vanilla-like odor. It is listed in CosIng with no restriction under Annexes I–III. The compound has been assessed by IFRA and shows low acute toxicity. It is not classified as a skin sensitizer under GHS, though as a phenolic compound it may cause mild irritation in sensitive individuals at high concentrations. EU allergen declaration applies if used as a fragrance compound at reportable levels.

Skin benefits

  • Provides vanilla-like fragrance in cosmetic formulations
  • Demonstrated antioxidant activity in vitro

Known concerns

  • EU fragrance allergen declaration may apply depending on source/IFRA usage
  • Mild skin irritation possible at high concentrations in sensitive individuals

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.