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1,3-Benzenediamine, 4-methyl-, hydrochloride (1:1)

CAS 5459-85-8
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

1,3-benzenediamine, 4-methyl-, Hydrochloride (1:1) is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

This aromatic diamine salt is closely related to the banned dihydrochloride form (30200) and serves as a primary intermediate in oxidative hair dyeing. Although less hazardous than the 1:2 salt, it remains a strong contact sensitizer requiring strict dose controls. The EU SCCS has evaluated toluene-2,5-diamine salts and established safe concentrations for hair dye use. Any cosmetic formulation must comply with the SCCS opinion and applicable Annex III limits.

Known concerns

  • Strong skin sensitizer potential
  • Requires compliance with EU SCCS safe concentration limits
  • Restricted to rinse-off hair dye applications in EU

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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Same plant / compound family

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.