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1-(4-Chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethylbutan-2-one

CAS 38083-17-9
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

This compound is climbazole, a broad-spectrum imidazole antifungal used as a cosmetic preservative. It appears in EU CosIng with concentration limits: 0.5% in rinse-off products, 0.2% in other product types. H302 (harmful if swallowed), H400 (very toxic to aquatic life), H410 (toxic to aquatic life with long-lasting effects), H412 (harmful to aquatic life with long-lasting effects) reflect environmental concerns rather than direct human toxicity at approved concentrations. At regulated levels, it is considered safe for rinse-off cosmetic use, though environmental persistence is a concern.

Skin benefits

  • Broad-spectrum antifungal preservative
  • Effective against Pityrosporum ( dandruff/pathology)
  • Extends product shelf life at low concentrations

Known concerns

  • Aquatic toxicity H400, H410, H412
  • Oral toxicity H302 at high doses
  • Restricted to specific product types and concentrations
  • Environmental persistence concern

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.