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2-Amino-4-nitrophenol

CAS 99-57-0
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

2-amino-4-nitrophenol is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

This amino nitrophenol serves as a coupler in oxidative hair dye systems. While permitted at controlled concentrations, it has demonstrated sensitization potential in dermatological testing. The nitro group is metabolically reducible to reactive intermediates, and its use is regulated under general cosmetic safety provisions in the EU.

Known concerns

  • Skin sensitization potential
  • Metabolic activation to reactive intermediates
  • Subject to concentration restrictions in hair dye formulations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.