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2-[(4-Methyl-2-nitrophenyl)azo]-3-oxo-N-phenylbutyramide

CAS 2512-29-0
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

A nitrophenylazo arylamide compound functioning as a direct dye, analogous to many restricted hair dye colorants. The nitro substituent and azo bond are pharmacophores associated with contact sensitization and potential to generate aromatic amines. Explicitly restricted to non-mucous-membrane products per EU Annex III entry under Commission Regulation (EU) 2017/695. Similar structural alerts apply as for other nitrobenzene azo hair dyes.

Known concerns

  • Nitro and azo groups are sensitization pharmacophores
  • EU Annex III restricted - not for mucous membranes
  • Potential to generate allergenic aromatic amine decomposition products
  • Label warnings mandatory in EU

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.