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2,6-Di-Tert-Butyl-4-Methylphenol

CAS 128-37-0
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

2,6-di-tert-butyl-4-methylphenol is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

2,6-Di-Tert-Butyl-4-Methylphenol (BHT) is listed in EU Annex III with specific concentration limits: 0.001% in fine fragrance, 0.1% in other rinse-off products, and 0.8% in other products. BHT has been associated with liver and kidney effects at higher exposures (H370, H373), aquatic toxicity (H400, H410), and contact sensitisation (H317). The SCCS has flagged cumulative exposure from multiple product types as a concern.

Skin benefits

  • Antioxidant — may help protect skin from oxidative stress

Known concerns

  • EU Annex III restricted — concentration limits apply by product type
  • Organ toxicity (liver/kidney) from repeated exposure (H370, H373)
  • Aquatic toxicant (H400, H410)
  • Contact sensitiser (H317)
  • Developmental/reproductive concern (H361)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.