4,5-DIAMINO-1-((4-CHLOROPHENYL)METHYL)-1H-PYRAZOLE-SULFATE
Other
Caution
CAS Number: 163183-00-4
About 4,5-DIAMINO-1-((4-CHLOROPHENYL)METHYL)-1H-PYRAZOLE-SULFATE
A hair dye intermediate used for oxidative colouring, this pyrazole derivative is restricted in the EU to authorised oxidative hair dye formulations due to its potential to cause skin sensitisation.
Detailed Analysis
This aromatic pyrazole sulfate functions as a primary intermediate in oxidative (permanent) hair dye systems. In the EU it is listed in Annex III (the positive list of substances restricted in cosmetic products), specifically entry 1218, with maximum concentration limits applied at the point of mixing for oxidative hair dye use. It carries a known risk of contact sensitisation and requires caution in handling.
Known Concerns
- ⚠ Skin sensitisation potential
- ⚠ EU Annex III restricted — authorised use only in oxidative hair dye formulations
- ⚠ Requires cautionary labelling and patch testing guidance
Safety Score
Caution
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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