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Prohibited hair dye intermediate

4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE

6

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

This compound belongs to the m-phenylenediamine family of hair dye intermediates that the EU has banned. These substances are known to trigger strong allergic skin reactions in many users.

Skin benefits

  • Was explored as a permanent hair dye coupler
  • Listed in the SCCS opinion database which reflects scientific scrutiny

Known concerns

  • Banned in EU cosmetics (Annex II) as an m-phenylenediamine derivative
  • m-Phenylenediamine class compounds are strong skin sensitizers
  • Risk of contact dermatitis and cross reactivity with PPD
  • Insufficient safety data to support cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related prohibited hair dye intermediates

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.