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4-FLUORO-6-METHYL-M-PHENYLENEDIAMINE SULFATE

CAS 173994-76-8 / 217311-43-8
27

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A fluorinated aromatic diamine hair dye intermediate with limited safety data, restricted in EU cosmetics due to concerns typical of aromatic diamine hair dye precursors.

4-Fluoro-6-methyl-m-phenylenediamine sulfate is a fluorinated aromatic diamine where the fluorine atom is substituted on the benzene ring. The fluorine substitution imparts unique electronic properties and can increase lipophilicity compared to non-fluorinated analogs. Like other aromatic diamine hair dye intermediates, it is restricted in EU cosmetic hair dye formulations under Regulation 1223/2009. Limited published safety data exist for this specific compound, contributing uncertainty to its risk assessment. The methyl substituent at position 6 adds to the structural complexity. Hair dye intermediates with fluorine substituents are subject to the same regulatory scrutiny as their non-fluorinated counterparts, with restrictions based on the aromatic diamine backbone rather than the specific substitution pattern.

Skin benefits

  • Hair dye intermediate for specialized color formulations with potential unique shade characteristics

Known concerns

  • EU hair dye intermediate — regulatory restrictions apply
  • Limited safety data available
  • Skin sensitization potential
  • Professional use only — concentration limits expected

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.