Other
4-Ethoxy-m-phenylenediamine and its salts
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Ethoxy-m-phenylenediamine and its salts is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.
4-Ethoxy-m-phenylenediamine and its salts are aromatic diamine hair dye intermediates with multiple CAS numbers reflecting various salt forms (sulfate, hydrochloride, etc.) and hydrates. The compounds carry hazard classifications H302 (harmful if swallowed), H315 (skin irritation), H319 (eye irritation), H341 (suspected mutagen), H351 (suspected carcinogen), and H411 (aquatic chronic toxicity). The ethoxy substituent modifies the electronic and solubility properties of the aromatic diamine. The combined mutagenicity and carcinogenicity classifications under EU Regulation 1223/2009 result in severe restrictions or prohibition in cosmetic products. These compounds require professional use only with strict adherence to maximum permitted concentrations in finished hair dye preparations.
Skin benefits
- Hair dye intermediate for specialized oxidation color formulations
Known concerns
- Suspected mutagen (H341)
- Suspected carcinogen (H351)
- EU hair dye restrictions apply
- Acute oral toxicity
- Environmental toxicity
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.