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5-ETHYL-3-HYDROXY-4-METHYLFURAN-2-ONE

CAS 698-10-2
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

5-ethyl-3-hydroxy-4-methylfuran-2-one is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

5-Ethyl-3-hydroxy-4-methylfuran-2-one is a hydroxyfuranone (a lactone-like structure) used primarily as a flavoring agent (fruity, caramel notes) in foods. Its H302 classification (harmful if swallowed) indicates acute oral toxicity concern. In cosmetic applications, the furanone structure raises metabolic concerns due to potential for furan ring opening to reactive intermediates. EU SCCS notes insufficient data for chronic cosmetic safety of furanone derivatives. The ingredient is not currently restricted under EU Annexes but is flagged for further safety assessment.

Known concerns

  • Acute oral toxicity (H302) - harmful if swallowed
  • Furan ring structure - potential for reactive metabolic intermediates
  • Limited chronic toxicity and sensitization data
  • Not evaluated by SCCS for cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.