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ACETYL HEXAMETHYL INDAN

CAS 15323-35-0
58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A polycyclic musk fragrance compound restricted in the EU due to environmental persistence and bioaccumulation concerns, limiting its use in cosmetic products.

Acetyl hexamethyl indan (AHMI, also known as 1,1,2,3,3-pentamethylindan-5-yl ethanone) is a synthetic polycyclic musk used as a fragrance ingredient. It is listed in EU Regulation (EC) No 1223/2009 Annex III with restriction III/134, which limits its concentration in ready-to-use cosmetic products due to environmental concerns. The compound is persistent, bioaccumulative, and toxic to aquatic organisms (H411). While not acutely toxic to humans, environmental restrictions significantly limit its use in EU-market cosmetics.

Known concerns

  • EU Annex III restricted (III/134) - environmental reasons
  • Aquatic chronic toxicity (H411)
  • Persistent and bioaccumulative potential

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.