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Skin Conditioning

ANNONA MURICATA LEAF EXTRACT

Updated
50

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Soursop (graviola) leaf extract — popular in traditional medicine, but the leaves carry annonaceous acetogenins linked to atypical parkinsonism with chronic oral exposure. Cosmetic use should be conservative.

Function

ANTIOXIDANT

Skin benefits

  • Antioxidant phenolics
  • Antimicrobial activity
  • Ethnobotanical record
  • Anti-inflammatory effect

Known concerns

  • Annonaceous acetogenins (neurotoxicity link)
  • Bioactive at low doses
  • Long-term-use concerns
  • Limited cosmetic dossier

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.