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Antioxidant

ANNONA MURICATA LEAF/STEM EXTRACT

Updated
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Graviola (soursop) leaf and stem extract — contains annonaceous acetogenins linked to atypical Parkinsonism in epidemiological studies. Cosmetic safety hinges on supplier acetogenin removal.

Function

SKIN CONDITIONING

Skin benefits

  • Phenolic antioxidant chemistry
  • Traditional Caribbean and Latin American medicinal use
  • Mild antimicrobial activity

Known concerns

  • Contains annonaceous acetogenins — neurotoxins linked to atypical Parkinsonism in epidemiology
  • Documented neurotoxicity from chronic graviola consumption
  • Cosmetic safety dependent on acetogenin removal
  • Limited cosmetic dossiers

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.