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Atropine, its salts and derivatives

CAS 51-55-8
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A potent tropane alkaloid with significant anticholinergic toxicity, absolutely banned in cosmetic products in the EU.

Atropine is a potent anticholinergic alkaloid derived from Atropa belladonna with profound effects on the parasympathetic nervous system. It is listed on EU Cosmetics Regulation Annex II (prohibited substances) due to its extreme toxicity (H300, H330) and pharmacological potency. Even minimal systemic absorption from topical application could cause serious adverse effects.

Known concerns

  • Banned in EU cosmetic products (Annex II)
  • Potent anticholinergic alkaloid
  • Acute oral toxicity (H300)
  • Acute inhalation toxicity (H330)
  • Risk of serious systemic effects

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.