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BENZOXONIUM CHLORIDE

CAS 19379-90-9
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A quaternary ammonium preservative and antimicrobial agent with restricted use in cosmetics due to sensitization potential.

Benzoxonium chloride is used for its antimicrobial and preservative properties; however, the EU has restricted its use under general cosmetic safety provisions due to documented skin sensitization cases. PubChem safety score of 50 reflects known concerns. It is not listed in EU Annex III by name but falls under the broader regulatory evaluation of benzalkonium chloride analogues, which are subject to concentration limits typically not exceeding 0.1% for leave-on products.

Skin benefits

  • Antimicrobial preservative — extends product shelf life

Known concerns

  • Known skin sensitizer and allergen
  • Respiratory irritant at high concentrations
  • EU concentration limit typically ≤0.1% for leave-on products

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.