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CILOSTAMIDE

CAS 68550-75-4
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A research-grade PDE3 inhibitor occasionally repurposed as a cosmetic active. Behaves as a small-molecule drug; using it in cosmetics raises real safety and regulatory questions.

Function

SKIN PROTECTING

Skin benefits

  • Marketed as anti-aging skincare active
  • Phosphodiesterase-3 inhibitor in research

Known concerns

  • Pharmaceutical-grade PDE3 inhibitor — bioactive drug
  • Not appropriate as a leave-on cosmetic
  • Limited cosmetic safety review
  • Potential systemic absorption concerns

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.