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Prohibited corticosteroid

clobetasol

CAS 25122-41-2
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A super-potent prescription steroid sometimes found illegally in skin lightening creams. It is banned from EU cosmetics and can thin skin, cause stretch marks, and disturb hormones with repeated use.

Skin benefits

  • Powerful prescription anti-inflammatory used medically for severe eczema and psoriasis
  • Rapid suppression of skin inflammation when used under doctor supervision
  • Effective for short-term medical treatment of inflammatory skin disorders

Known concerns

  • Prohibited in EU cosmetics under Regulation 1223/2009; prescription-only corticosteroid
  • GHS H360: may damage fertility or the unborn child
  • Causes skin thinning, telangiectasia, stretch marks, adrenal suppression with cosmetic misuse
  • Frequently found illegally in skin lightening creams sold as cosmetics
  • GHS H373: may damage organs through prolonged or repeated exposure

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.