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4,4'-DIAMINODIPHENYLAMINE SULFATE

CAS 6369-04-6
40

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An aromatic amine used primarily in hair dye formulations with EU restrictions due to skin sensitization and acute toxicity concerns.

4,4'-Diaminodiphenylamine sulfate (CAS 6369-04-6) carries EU restriction II/1309, indicating it is permitted in cosmetic products but with specific constraints, likely as a hair dye intermediate. Hazard statements include H302 (acute oral toxicity), H312 (dermal toxicity), H315 (skin irritation), H319 (eye irritation), and H332 (inhalation toxicity). Hair dye intermediates in this class are known skin sensitizers and require appropriate use level controls.

Known concerns

  • Acute toxicity (H302, H312, H332)
  • Skin and eye irritation (H315, H319)
  • EU restricted (II/1309)
  • Known skin sensitizer

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.