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2-NITRO-5-GLYCERYL METHYLANILINE

CAS 80062-31-3
40

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

2-nitro-5-glyceryl Methylaniline is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

2-Nitro-5-glyceryl methylaniline is a nitro-substituted aniline derivative bearing a glyceryl ether substituent, used as a coupling agent in oxidative hair dye formulations. Its toxicological profile is characterised by the nitro group (potential reductive activation) and the aromatic amine (potential sensitisation). It is not currently listed in EU Annex II restrictions, though its structural alerts warrant caution and further safety assessment. Cosmetic use remains limited to hair dye applications.

Known concerns

  • Nitro group with potential reductive metabolic activation
  • Aromatic amine sensitisation potential
  • Limited comprehensive toxicological data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.