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BASIC RED 46

CAS 12221-69-1
40

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic permanent hair dye with EU regulatory restrictions (Annex II/1259) and documented skin sensitization potential, requiring careful handling and rinse-off use.

Basic Red 46 is a synthetic cationic diazo dye used primarily in oxidative hair dye formulations. It carries a CosIng restriction notation (II/1259) and has a PubChem safety score of 42, indicating moderate concern. Hair dye ingredients are among the most regulated cosmetic substances in the EU, requiring batch certification and specific labeling. It is restricted to professional use in many formulations.

Known concerns

  • EU Annex II/1259 restricted hair dye
  • Known to cause skin sensitization in some users
  • Restricted to professional use formulations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.