Solvent
DIMETHOXYDIGLYCOL
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
Diglyme — a glycol-ether solvent flagged by EU CLP as a reproductive toxicant (H360). Strongly avoided in modern cosmetics; safer ether solvents have replaced it.
Function
Skin benefits
- Powerful aprotic solvent and viscosity modifier
- Stable in many formulations
- Industrial co-solvent
Known concerns
- GHS H360 may damage fertility or unborn child
- H361 suspected reproductive toxicity
- H226 flammable, H335 respiratory irritant — generally avoided in modern cosmetics
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related solvents
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.