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Solvent

METHYL PYRROLIDONE

CAS 872-50-4 Updated
12

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

N-methyl-2-pyrrolidone (NMP), an aprotic solvent classified as a reproductive toxicant under EU REACH. Inappropriate for cosmetic use due to fetal-toxicity concerns.

Function

SOLVENT

Skin benefits

  • Powerful solvent and penetration enhancer
  • Used at low % to dissolve hard-to-formulate actives
  • Industrially significant for film/coating tech

Known concerns

  • EU REACH restricted — reproductive toxicant
  • GHS H360D — may damage the unborn child
  • H315 skin / H319 eye / H335 respiratory irritation
  • SCCS does not endorse for cosmetic leave-on use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related solvents

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.