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Solvent

bis(2-Methoxyethyl) ether (Dimethoxydiglycol)

CAS 111-96-6 Updated
12

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A glycol-ether solvent (diglyme) classified as a reproductive toxicant in the EU and restricted at and above 0.1 percent in cosmetics. Considered inappropriate for skin-contact products.

Skin benefits

  • Primarily a processing aid

Known concerns

  • EU-classified reproductive toxicant (CMR) — Annex II / Annex III restriction with 0.1% threshold
  • Risk of harm to the unborn child
  • Not appropriate for cosmetic use
  • Volatile glycol ether with respiratory and dermal absorption concerns

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related solvents

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.