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Disodium 5-acetylamino-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonate

CAS 3734-67-6
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An anionic azo dye (Acid Red 1 / C.I. 18050) permitted in cosmetics but explicitly excluded from use on mucous membranes under EU restrictions.

C.I. Acid Red 1 (CAS 3734-67-6) is a synthetic anionic azo dye commonly used in colourant applications. EU Regulation 1223/2009 Annex III restricts this substance specifically from products applied on mucous membranes due to potential absorption concerns. The compound contains a phenylazo group, which under reductive cleavage conditions can release aromatic amines — a key regulatory concern for all azo colourants in the EU.

Known concerns

  • EU restriction — not to be used on mucous membranes
  • Azo dye — potential amine cleavage under reducing conditions
  • Absorption concern on sensitive epithelia

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.