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ETHYL METHYLBUTYL KETOXIME

CAS 22457-23-4
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Ethyl Methylbutyl Ketoxime is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Ethyl methylbutyl ketoxime (also called ethyl sec-butyl ketoxime or 2-butanone oxime derivative; CAS 22457-23-4) is an oxime compound used as an anti-skinning agent and corrosion inhibitor in industrial paints and coatings. Oxime compounds are known skin sensitizers and have been associated with allergic contact dermatitis in occupational settings. The compound is not listed in EU Annex II or III under Regulation 1223/2009, and it is not a common cosmetic ingredient — its presence in a cosmetic ingredient batch is unusual and raises formulation integrity concerns. There is no IFRA evaluation for this material in cosmetics. The safety score is set in the 40–59 range reflecting its known sensitization hazard and absence of cosmetic-specific safety data.

Skin benefits

  • No established cosmetic skin benefits; industrial anti-skinning agent only

Known concerns

  • Documented skin sensitizer in occupational/industrial settings
  • Known allergic contact dermatitis hazard
  • No IFRA or SCCS cosmetic safety evaluation
  • Unsuitable for cosmetic formulations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.