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Skin Conditioning

GLYCYRRHIZA URALENSIS CALLUS EXTRACELLULAR VESICLES

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Plant-callus vesicles from Chinese liquorice (Glycyrrhiza uralensis). Carries the herb’s soothing/anti-redness signature in nano-vesicle form.

Glycyrrhiza uralensis callus extracellular vesicles are nanoscale lipid vesicles isolated from plant cell cultures of Chinese liquorice. Glycyrrhiza extracts and licorice constituents (glycyrrhizin, glabridin) are widely used in cosmetics for soothing, anti-redness, and brightening effects, with a long topical safety record. The vesicle preparation is novel and lacks SCCS or CIR review; toxicology rests on supplier data. Liquorice can rarely sensitise allergic users.

Function

SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

Skin benefits

  • Plant-derived soothing and antioxidant signalling
  • Vegan, sustainable callus source
  • Generally low irritation

Known concerns

  • Novel ingredient with no SCCS or CIR opinion
  • Glycyrrhiza-allergic users may react
  • Supplier-driven efficacy claims

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.