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HC ORANGE NO. 2

CAS 85765-48-6
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Hc Orange No. 2 is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

HC Orange No. 2 is listed in EU Annex III/208 of Cosmetics Regulation 1223/2009, indicating restricted use in hair dye products. The compound carries structural alerts for skin and respiratory sensitisation consistent with its nitroaniline chemical class. Dermatological studies have documented positive patch test reactions in individuals with contact allergy to hair dye systems. The restriction in EU Annex III requires compliance with specific conditions of use including concentration limits, and the compound is excluded from use in eye and eyebrow products.

Known concerns

  • EU Annex III/208 restricted — concentration limits apply
  • Skin sensitisation (H317 risk)
  • Excluded from eye and eyebrow products
  • Contact allergy documented

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.