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HEMATIN

CAS 15489-90-4
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Hematin is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Hematin is the iron-containing prosthetic group of heme proteins, derived from the porphyrin ring structure. It has been used in some dermatological and hair care applications but its cosmetic use history is limited. Safety data for topical application is sparse, and the iron-catalyzed redox properties of hematin raise theoretical concerns about oxidative stress at high concentrations. It is not clearly listed in CosIng with an approved function.

Skin benefits

  • May support oxygenation in topical context (theoretical)
  • Historical use in hair care preparations

Known concerns

  • Limited cosmetic safety data
  • Iron-mediated redox activity may generate oxidative stress
  • Not clearly listed in EU CosIng as approved cosmetic ingredient
  • Potential for metal-induced sensitization

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.