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Synthetic peptide active

HEXAPEPTIDE-65

80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic hexapeptide used in anti-ageing skin care for signalling effects on dermal proteins. Peptides of this class are typically well tolerated, though efficacy data are largely supplier-driven.

Function

ANTIOXIDANT, SKIN PROTECTING

Skin benefits

  • Synthetic signal peptide marketed for anti-ageing and firmness
  • Low molecular weight peptides have favorable tolerance
  • Generally non-irritating at use levels

Known concerns

  • Specific in vivo efficacy claims rely largely on supplier studies
  • Limited independent peer-reviewed data
  • Stability in finished formula can be variable

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related synthetic peptide actives

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TETRAPEPTIDE-44
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HEXAPEPTIDE-91
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OCTAPEPTIDE-42
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PENTAPEPTIDE-93
Synthetic peptide active

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.