Skin Conditioning
HEXAPEPTIDE-65
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Hexapeptide-65 — another proprietary signalling hexapeptide. Plausible mechanism, low-exposure, supplier-heavy evidence.
Hexapeptide-65 is a synthetic six-amino-acid peptide used in cosmetics for skin-conditioning and anti-ageing claims. Listed in EU CosIng; no SCCS opinion. Use levels typically in the parts-per-million range. Public toxicological literature is limited; supplier dossiers provide most in-vitro and small in-vivo tolerance data. Evidence level low. Standard profile for a modern proprietary peptide.
Function
Skin benefits
- Synthetic signalling peptide
- Low-use-level exposure
- Short-term tolerance
Known concerns
- Thin public safety data
- No SCCS dossier
- Proprietary evidence
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
Check your shelf
Find HEXAPEPTIDE-65 in your products.
Scan any cosmetic product with LuxSense to see if it contains HEXAPEPTIDE-65 and get a full ingredient breakdown with safety scores.
This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.