Skin Conditioning
OCTAPEPTIDE-42
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A synthetic eight-amino-acid peptide used as a skin-conditioning agent. Designer peptide with sparse independent safety literature; typically dosed at ppm levels.
Octapeptide-42 is an eight-residue synthetic peptide developed for skin-conditioning cosmetic applications. Octapeptides in cosmetic use are dosed at very low concentrations and are generally considered low-irritation due to poor stratum corneum penetration and rapid enzymatic degradation. Independent regulatory review (CIR/SCCS) of this specific INCI is not yet available; efficacy claims come predominantly from the supplier. The INCI is listed in EU CosIng. Conservative tier: yellow with low evidence pending independent data.
Function
Skin benefits
- Skin-conditioning at trace concentrations
- Low irritation potential
- Suitable for most leave-on formats
Known concerns
- Limited independent safety data
- No CIR or SCCS review
- Efficacy depends on supplier-controlled studies
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.