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Synthetic peptide active

HEXAPEPTIDE-85 HYDROXYPROLINE

80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Hexapeptide-85 hydroxyproline is a lab-made signal peptide pairing six amino acids with hydroxyproline, marketed to support collagen-related smoothness. Topically applied peptides are typically well tolerated.

Function

ANTIOXIDANT, SKIN CONDITIONING - MISCELLANEOUS

Skin benefits

  • Synthetic peptide designed to support skin firmness
  • Combined with hydroxyproline, a collagen building block
  • Generally non-irritating at use levels
  • Marketed for fine-line and elasticity benefits

Known concerns

  • Efficacy claims often outpace independent clinical evidence
  • Limited public toxicology data for this specific hexapeptide

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related synthetic peptide actives

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.