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Synthetic peptide active

TETRAPEPTIDE-44

80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic tetrapeptide used as a signalling active in anti-ageing skin care. Peptides of this class are well tolerated in cosmetics, though independent efficacy data are limited.

Function

SKIN CONDITIONING

Skin benefits

  • Short synthetic peptide marketed for skin-renewal signalling
  • Tetrapeptides typically have a favourable irritation profile
  • Used in anti-ageing serums

Known concerns

  • Efficacy evidence largely from supplier-funded studies
  • Stability in finished products varies
  • Few independent peer-reviewed reviews

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related synthetic peptide actives

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HEXAPEPTIDE-65
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HEXAPEPTIDE-85 HYDROXYPROLINE
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HEXAPEPTIDE-91
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OCTAPEPTIDE-42
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PENTAPEPTIDE-93
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.