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HYDROXYLAUROYL PHYTOSPHINGOSINE

CAS -
82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Hydroxylauroyl Phytosphingosine is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Hydroxylaupoyl phytosphingosine is a conjugate of 12-carbon hydroxylated fatty acid (hydroxylauric acid) with phytosphingosine. Like its C8 counterpart (hydroxycapryloyl phytosphingosine), it is a skin-identical ingredient. The longer C12 fatty acid chain may provide enhanced occlusion and lipid barrier reinforcement compared to shorter-chain variants. Published research supports the use of phytosphingosine derivatives in skin barrier repair, eczema management, and anti-aging formulations. The EU CosIng database lists phytosphingosine derivatives as approved cosmetic ingredients with no restrictions. The compound demonstrates excellent safety across skin types with no sensitization or irritation signals in available data.

Skin benefits

  • Reinforces stratum corneum lipid barrier
  • Reduces transepidermal water loss (TEWL)
  • Anti-inflammatory and soothing properties
  • Antimicrobial activity
  • Supports ceramide synthesis in skin
  • Particularly beneficial for dry, sensitive, and compromised skin

Known concerns

  • Extremely well-tolerated with minimal concerns
  • Natural skin lipid - compatible with all skin types

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.